vestichИзвестия Национальной академии наук Беларуси. Серия химических наукProceedings of the National Academy of Sciences of Belarus, Chemical Series1561-83312524-2342The Republican Unitary Enterprise Publishing House "Belaruskaya Navuka"10.29235/1561-8331-2026-62-2-142-154vestich-1017Research ArticleХИМИЯ ВЫСОКОМОЛЕКУЛЯРНЫХ СОЕДИНЕНИЙPOLYMER CHEMISTRYИнтерполиэлектролитные комплексы нанокомпозита хитозан-серебро с пектином и его производными и пористые материалы на их основеInterpolyelectrolyte complexes of chitosan-silver nanocomposite with pectin and its derivatives and porous materials based on themhttps://orcid.org/0000-0002-3657-1353НиколайчукВ. В.NikalaichukV. V.

Николайчук Виктория Викторовна – аспирант, научный сотрудник.

Ул. Ф. Скорины, 36, 220084, Минск

Nikalaichuk Viktoryia V. – Postgraduate Student, Researcher.

36, F. Skorina Str., 220084, Minsk

vica10bcn@gmail.comhttps://orcid.org/0000-0001-6505-3929КуликовскаяВ. И.KulikouskayaV. I.

Куликовская Виктория Игоревна – кандидат химических наук, доцент, заведующий лабораторией.

Ул. Ф. Скорины, 36, 220084, Минск

Kulikouskaya Viktoryia I. – Ph. D. (Chemistry), Associate Professor, Head of the Laboratory.

36, F. Skorina Str., 220084, Minsk

kulikouskaya@gmail.comhttps://orcid.org/0000-0002-0024-1424КонгДу ВанCongDo Van

Ду Ван Конг – доктор химических наук, главный исследователь.

Ул. Хоанг Куок Вьет, 18, район Каугиай, Ханой

Do Van Cong – Dr. Sci. (Chemistry), Principal Investigator.

18, Hoang Quoc Viet Street, CauGiay District, Hanoi

dvcong@ism.vast.vnИнститут химии новых материалов Национальной академии наук БеларусиБеларусьInstitute of Chemistry of New Materials of the National Academy of Sciences of BelarusBelarusИнститут материаловедения Вьетнамской академии наук и технологииВьетнамInstitute of Materials Science, Vietnam Academy of Science and TechnologyViet Nam202626052026622142154Copyright © Николайчук В.В., Куликовская В.И., Конг Д., 20262026Николайчук В.В., Куликовская В.И., Конг Д.Nikalaichuk V.V., Kulikouskaya V.I., Cong D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestichem.belnauka.by/jour/article/view/1017

Изучены закономерности формирования и антиоксидантная активность интерполиэлектролитных комплексов (ИПЭК) на основе нанокомпозитов хитозан-серебро, пектин-серебро, пектина и окисленного пектина. Разработана методика получения пористых материалов на основе ИПЭК и определены параметры, позволяющие регулировать их структуру и физико-химические свойства. Матрицы на основе ИПЭК характеризуются высокой пористостью (> 95 %) и плотностью (от 15,5 до 28,8 мг/см3). Установлено, что основное влияние на степень деградации пористых материалов в исследуемом временном промежутке (до 7 суток) оказывает качественный состав комплексов (тип полианиона в ИПЭК). Образцы на основе окисленного пектина продемонстрировали наилучшую устойчивость в модельной среде (фосфатно-солевой буфер Дульбекко), сохранив форму и целостность, при этом средняя потеря массы образцов составила 23,4 ± 10,0 %. Полученные пористые материалы на основе ИПЭК могут представлять практический интерес для применения в составе раневых покрытий в качестве активного слоя, несущего антибактериальную и антиоксидантную функции.

The paper studies the regularities of formation and antioxidant activity of interpolyelectrolyte complexes (IPECs) based on chitosan-Ag and pectin-Ag nanocomposites, as well as pectin and oxidized pectin. The technique for fabricating porous IPEC-based materials has been developed, and parameters allowing to regulate their structure and physicochemical properties have been determined. IPEC-based matrices are characterized by high porosity (> 95 %) and a density ranging from 15.5 to 28.8 mg/cm3. It has been established that the qualitative composition of the complexes (the type of polyanion in IPECs) has the main effect on the degree of degradation of the porous materials under the studied time period (up to 7 days). Samples based on oxidized pectin demonstrated the best stability in a model medium (Dulbecco’s phosphate-buffered saline), retaining their shape and integrity, while their average mass loss was 23.4 ± 10.0 %. The obtained porous materials based on IPECs may be of practical interest for application in wound dressings as an active layer carrying antibacterial and antioxidant functions.

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The authors declare that there are no conflicts of interest present.