Synthesis of composite materials based on calcium phosphates and blood components
https://doi.org/10.29235/1561-8331-2019-55-2-135-141
Abstract
Composites based on calcium phosphates in the matrix of biopolymer (citrated plasma and fibrin) were synthesized in neutral and alkaline medium. At pH 7 brushite composites were obtained, whereas at pH 11 amorphized hydroxyapatite was precipitated. Disruption of precipitation conditions led to the formation of tricalcium phosphate impurity, which was detected by XRD after thermal treatment of composites at 800 °C. Composition and morphology of calcium phosphates did not depend on biopolymer nature. To determine bioactivity degree, composites were incubated in model Simulated Body Fluid (SBF) for 75 days. It was found that composites based on amorphized hydroxyapatite incorporated in biopolymer matrix have maximum growth of biomimetic layer of apatite.
About the Authors
I. E. Glazov
Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Ilya E. Glazov – Junior researcher
9/1, Surganov Str., 220072, Minsk
R. A. Vlasov
Republican Hospital of the Department of Finance and Logistics of the Ministry of Internal Affairs of Republic of Belarus
Belarus
Belarus
Roman A. Vlasov – ENT specialist
4, Zolotaya gorka Str, 220005, Minsk
V. K. Krut’ko
Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Valentina K. Krut’ko – Ph. D. (Chemistry), Associate Professor, Leading researcher
9/1, Surganov Str., 220072, Minsk
O. N. Musskaya
Institute of General and Inorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Olga N. Musskaya – Ph. D. (Chemistry), Associate Professor, Senior researcher
9/1, Surganov Str., 220072, Minsk
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