Аn improved method for preparation of heptyl (4-trifluoroacetyl) benzoate
https://doi.org/10.29235/1561-8331-2019-55-2-171-174
Abstract
A convenient three-step method for synthesis of heptyl (4-trifluoroacetyl)benzoate, an important neutral anion carrier, has been developed. The key step of the method is acylation of toluene by trifluoroacetic anhydride in presence of aluminium chloride at –8 – –10 oC. The procedure gives high overall yield and, unlike the earlier methods, does not include any organometallic reagents, therefore allowing scaling it up to several hundred grams, that makes the target compound much more readily available.
About the Authors
P. V. Senin
Atotech-Khemeta Ltd.
Russian Federation
Russian Federation
Pavel V. Senin – Sales Engineer, Atotech-Khemeta Ltd.
73, Volokolamskoe Highway, offce 623, 125424, Moscow
L. S. Stanishevskii
Belarusian State University
Belarus
Leonid S. Stanishevskii – D. Sc. (Chemistry), Professor
Belarus
Leonid S. Stanishevskii – D. Sc. (Chemistry), Professor
Y. B. Akayeu
Belarusian State University
Belarus
Belarus
Yauhen B. Akayeu – Ph. D. (Chemistry), Associate Professor, Leading Researcher
14, Leningradskaya Str., 220030, Minsk
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