Testing of experimental samples of sorbents based on aromatic peptides
https://doi.org/10.29235/1561-8331-2020-56-4-465-472
Abstract
By dynamic experiments, the purpose of which was to establish the time during which the saturation of sorbents occurs, as well as the maximum amount of total IgG bound, the saturation and capacity properties were revealed. Sorption dynamics data have been obtained for tripeptides: Phe-Trp-DTyr, Trp-Phe-DTyr, Phe-Ala-Tyr-OMe, Phe-Asn-Tyr-OMe, Phe-Asp (Bzl)-Tyr-OMe, Phe-Gln-Tyr-OMe and Phe-Gly-Tyr. Specific saturation was reliably confirmed for the Phe-Trp-DTyr sample and the Phe-Gln-Tyr-OMe sample. Other samples of sorbents show positive dynamics with episodic periods of desorption, with further alignment of the positive dynamics of the sorption process.
About the Authors
Y. S. Pustsyulga
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Russian Federation
Russian Federation
Yegor S. Pustyulga – Researcher.
5/2, Acad. V. F. Kuprevich Str., 220141, Minsk
O. V. Gribovskaya
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Russian Federation
Russian Federation
Olga V. Gribovskaya - Senior Researcher.
5/2, Acad. V. F. Kuprevich Str., 220141, Minsk
E. M. Ermola
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Russian Federation
Russian Federation
Eugeny M. Ermola - Researcher.
5/2, Acad. V. F. Kuprevich Str., 220141, Minsk
V. P. Golubovich
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus
Russian Federation
Russian Federation
Vladimir P. Golubovich - D. Sc. (Biology), Professor, Head of the Laboratory.
5/2, Acad. V. F. Kuprevich Str., 220141, Minsk
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