Synthesis of S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole
https://doi.org/10.29235/1561-8331-2021-57-3-294-299
Abstract
Condensed indole derivatives of the 1,2,4-triazino[5,6-b]indole group show high biological activity and are of interest for the development of pharmaceuticals that have antihypoxic and antisurditant effects. By S-aminoalkylation reactions on a thione group, S-aminoalkyl derivatives of 1,2,4-triazino[5,6-b]indole-3-thione that were subject to hydrobromination in order to obtain the form of hydrobromides were synthesized, isolated and characterized.
About the Authors
D. V. Lopatik
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Dina V. Lopatik – Ph. D. (Chemistry), Senior Researcher
13, Surganov Str., 220072, Minsk
Z. I. Kuvaeva
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Zoya I. Kuvaeva – D. Sc. (Chemistry), Professor, Head of the Department
13, Surganov Str., 220072, Minsk
V. E. Naidenov
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Vladimir E. Naidenov – Researcher
13, Surganov Str., 220072, Minsk
O. M. Bondareva
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Olga M. Bondareva – Researcher
13, Surganov Str., 220072, Minsk
L. Yu. Tychinskaya
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Lyudmila Yu. Tychinskaya – Leading Researcher
13, Surganov Str., 220072, Minsk
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