Synthesis of N-aryl and pyridine-substituted derivatives of valine, leucine and isoleucine
https://doi.org/10.29235/1561-8331-2024-60-2-145-152
Abstract
A preparative method for the synthesis of N-aryl- and pyridine-substituted valine, leucine, isoleucine derivatives by condensation of amino acids sodium salts with benzaldehyde, salicylaldehyde, vanillin, p-chlorobenzaldehyde, 3-pyridinecarbaldehyde and subsequent reduction with sodium borohydride has been developed.
About the Authors
Е. А. Akishina
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Akishina Ekaterina A. – Researcher
13, Surganov Str., 220072, Minsk
V. А. Knizhnikov
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Knizhnikov Valeriy A. – D. Sc. (Chemistry)
L. А. Popova
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Popova Ludmila A. – Senior Researcher
13, Surganov Str., 220072, Minsk
Е. G. Karankevich
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Karankevich Elena G. – Ph. D. (Chemistry), Head of the Laboratory
13, Surganov Str., 220072, Minsk
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