Synthesis of atophane-containing benzocyclopentaquinolines, benzacridines and bisbenzacridines
https://doi.org/10.29235/1561-8331-2025-61-1-65-72
Abstract
Atophane-containing benzocyclopentaquinolines and benzacridines were obtained by the reaction of cascade three-component condensation of atophane-containing esters of substituted benzaldehydes, 1.3-cycloalkyldiketones and 2-naphthylamine with a yield of 60−88 %. Atophane-containing bisbenzacridines were synthesized by a similar technique using 1.5-diaminonaphthalene with a yield of 50−80 %.
Keywords
atophane,
hydroxybenzaldehyde esters,
2-naphthylamine,
1.5-diaminonaphthalene,
cascade three-component condensation,
benzocyclopentaquinolines,
benzacridines,
bisbenzacridines
Supporting agencies: The work was carried out with financial support from the Belarusian Republican Foundation for Fundamental Research (grant № X22-038).
About the Authors
E. A. Dikusar
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Dikusar Evgenij A. – Ph. D. (Chemistry), Senior Researcher
13, Surganov Str., 220072, Minsk
E. A. Akishina
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Akishina Ekaterina A. – Researcher
13, Surganov Str., 220072, Minsk
S. S. Koval’skaya
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Koval’skaya Svetlana S. – Ph. D. (Chemistry), Senior Researcher
13, Surganov Str., 220072, Minsk
S. G. Stepin
Vitebsk State Order of Peoples’ Friendship Medical University
Belarus
Belarus
Stepin Svjatoslav G. – Ph. D. (Chemistry), Associate Professor, Head of the Department
17, Frunze Ave., 210023, Vitebsk
V. I. Potkin
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Potkin Vladimir I. – Academician, Dr. Sc. (Chemistry), Professor, Head of the Laboratory
13, Surganov Str., 220072, Minsk
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