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AN ENZYME IMMUNOASSAY OF FUMONISINS B IN FEEDS AND FOODS

https://doi.org/10.29235/1561-8331-2018-54-2-180-189

Abstract

A reagent kit EIA-FUMONISIN for the determination of mycotoxins of fumonisin B group in feeds and foods by a direct competitive enzyme immunoassay using microtitration plate has been developed and tested. The evaluated technicoanalytical parameters of the kit and metrological characteristics of the technique of measurements correspond to the mo- dern level of immunoassay development and provide the determination of fumonisin group B content of agricultural products in a range of 0.11 to 6.0 mg/kg with proper accuracy and precision.

About the Authors

L. V. Dubovskaya
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Ludmyla V. Dubovskaya – Senior researcher.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



I. V. Gorbacheva
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Irina V. Gorbacheva – Junior researcher.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



O. S. Kuprienko
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Olga S. Kuprienko – Researcher.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



A. A. Yastrebova
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Anna A. Yastrebova – Researcher.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



I. I. Vashkevich
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Irina I. Vashkevich – Ph. D. (Chemistry), Leading researcher.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



G. S. Kornilovich
Central Research Laboratory of Grain Products.
Belarus

Galina S. Kornilovich – Deputy Director for Science.

Minsk reg., 222220, Smolevichi distr., Oktyabrsky vil.



L. N. Sukhenko
Central Research Laboratory of Grain Products.
Belarus

Liliya N. Sukhenko – Head of the Department.

Minsk reg., 222220, Smolevichi distr., Oktyabrsky vil.



A. I. Shibeko
Central Research Laboratory of Grain Products.
Belarus

Anna I. Shibeko – Leading Chemical Engineer.

Minsk reg., 222220, Smolevichi distr., Oktyabrsky vil.



O. V. Sviridov
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus.
Belarus

Oleg V. Sviridov – D. Sc. (Chemistry), Senior Researcher, Head of the Laboratory.

5/2, Academician V. F. Kuprevich Str., 220141, Minsk.



References

1. Rheeder J. P., Marasas W. F. O., Vismer H. F. Production of Fumonisin Analogs by Fusarium Species. Applied and Environmental Microbiology, 2002, vol. 68, no. 5, pp. 2101–2105. Doi: 10.1128/aem.68.5.2101–2105.2002

2. Burkin A. A., Kononenko G. P. Fusariotoxins content in maize and rice grain harvested in the main regions of cultivation in the Russian Federation. Sel’skokhozyaistvennaya biologiya = Agricultural biology, 2008, no. 5, pp. 88–90 (in Russian).

3. Weidenborner М. Encyclopedia of food mycotoxins. Berlin Heidelberg, Springer–Verlag, 2001. 294 p. Doi: 10.1007/ 978–3–662–04464–3

4. Voss K. A., Riley R. T., Snook M. E., Waes J. G. Reproductive and sphingolipid metabolic effects of fumonisin B1 and its alkaline hydrolysis product in LM/Bc mice: hydrolyzed fumonisin B1 did not cause neural tube defects. Toxicological Sciences, 2009, vol. 112, pp. 459–467. Doi: 10.1093/toxsci/kfp215

5. Wild C. P., Gong Y. Y. Mycotoxins and human disease: a largely ignored global health issue. Carcinogenesis, 2010, vol. 31, no. 1, pp. 71–82. Doi: 10.1093/carcin/bgp264

6. Gelderblom W. C., Kriek N. P., Marasas W. F., Thiel P. G. Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. Carcinogenesis, 1991, vol. 12, no. 7, pp. 1247–1251. Doi: 10.1093/carcin/12.7.1247

7. Voss K. A., Riley R. T., Norred W. P., Bacon C. W., Meredith F. I., Howard P. C., Plattner R. D., Collins T. F., Hansen D. K., Porter J. K. An overview of rodent toxicities: liver and kidney effects of fumonisins and Fusarium moniliforme. Environmental Health Perspectives, 2001, vol. 109, no. S2, pp. 259–266. Doi: 10.1289/ehp.01109s2259

8. Waes G. J., Starr L., Maddox J., Aleman F., Voss K. A., Wilberding J., Riley R. T. Maternal fumonisin exposure and risk for neural tube defects: Mechanisms in an in vivo mouse model. Birth Defects Research Part A: Clinical and Molecular Teratology, 2005, vol. 73, no. 7, pp. 487– 497. Doi: 10.1002/bdra.20148

9. Missmer S. A., Suarez L., Felkner M., Wang E., Merrill A. H. Jr., Rothman K. J., Hendricks K. A. Exposure to fumonisins and the occurrence of neural tube defects along the Texas-Mexico border. Environmental Health Perspectives, 2006, vol. 114, no. 2, pp. 237–241. Doi: 10.1289/ehp.8221

10. Vashkevich I. I., Terentieva T. V., Kornilovich G. S., Sukhenko L. N., Shibeko A. I., Sviridov O. V. New reagent kit for enzyme immunoassay of aflatoxin B1 in feeds and foods. Vestsі Nacyyanal’naj akademіі navuk Belarusі. Seryya khіmіchnykh navuk = Proceedings of the National Academy of Sciences of Belarus. Chemical Series, 2016, no. 2, pp. 69–75 (in Russian).

11. Veterinary and sanitary rules to ensure safety of feed, feed additives and raw materials for feed producton, approved by the Decree of the Ministry of Agriculture and Food of the Republic of Belarus from 10.02.2011, no. 10.

12. Konopel’ko L. A. (ed.). Quantifying Uncertainty in Analytical Measurement. St. Petersburg, D.I. Mendeleyev Institute for Metrology (VNIIM), 2002. 149 p. (in Russian).

13. Barwick V. J., Ellison S. VAM Project 3.2.1. Development and Harmonisation of Measurement. Uncertainty Principles. Part (d): Protocol for uncertainty evaluation from validation data. LGC (Teddington) Ltd, 2000. 87 p.

14. Dubovskaya L. V., Sleptsova N. M., Epshteyn T. V., Vashkevich I. I., Sviridov O. V. Comparison of different methods of immobilization of monoclonal antibodies for solid competitive analysis. Vestsі Nacyyanal’naj akademіі navuk Belarusі. Seryya khіmіchnykh navuk = Proceedings of the National Academy of Sciences of Belarus. Chemical Series, 2007, no. 4, pp. 78–82 (in Russian).

15. State Standard 31653–2012. The method of enzyme immunoassay to determine mycotoxins. Moscow, Interstate council for standardization, metrology and certification: Federal agency for technical regulation and metrology, 2012. 12 p. (in Russian).

16. Instructions for the quantitative determination of fumonisin in feed and food products using the RIDASCREEN®FAST Fumonisin. Available at: https://food.r–biopharm.com/products/ridascreenfast–fumonisin/ (accessed 31 December 2017).


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ISSN 1561-8331 (Print)
ISSN 2524-2342 (Online)