Synthesis and cardioprotective effectiveness of arginine succinates
https://doi.org/10.29235/1561-8331-2020-56-2-181-186
Abstract
The synthesis was developed and physic-chemical properties of the pharmaceutical substance the di-L-arginine succinate were determined. Its cardioprotective effectiveness in cases of ischemic-reperfusion injury of the myocardium was demonstrated in experiments on rats. The substance was used to obtain the drug Inokardin of cardioprotective action.
About the Authors
D. V. Lopatik
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Dina V. Lopatik – Ph. D. (Chemistry), Senior Researcher
13, Surganov Str., 220072, Minsk
Z. I. Kuvaeva
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Zoya I. Kuvaeva – D. Sc. (Chemistry), Professor, Head of the Department
13, Surganov Str., 220072, Minsk
O. M. Bondareva
Institute of Physical Organic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Olga M. Bondareva – Researcher
13, Surganov Str., 220072, Minsk
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