Synthesis of spin-labeled emoxypine, methionine, o-anisidine
https://doi.org/10.29235/1561-8331-2020-56-2-192-196
Abstract
Spin-labeled (acylated with 4-doxylpentanoic acid) emoxypine, methionine, o-anisidine were synthesized. The compounds obtained were characterized using nuclear magnetic resonance spectroscopy, electron paramagnetic resonance spectroscopy, infrared and ultraviolet spectroscopy and mass spectrometry. Synthesized spin-labeled compounds can be used for biochemical studies using EPR spectroscopy.
Keywords
nitroxides,
spin labels,
4-doxylpentanoic acid,
antioxidants,
emoxypine,
methionine,
о-anisidine,
EPR spectroscopy
Supporting agencies: This work has been supported by the Belarusian Republican Foundation for Fundamental Research (contract № X17M-104 dated 04/18/2017).
About the Authors
M. V. Lisouskaya
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Maryna V. Lisouskaya – Junior Researcher
5/2, Academician Kuprevich Str., 220141, Minsk
N. V. Kot
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Natalya V. Kot – 1st category chemist-pharmacist, Scientific-Production Centre “ChemPharmSynthesis”
5/2, Academician Kuprevich Str., 220141, Minsk
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