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Proceedings of the National Academy of Sciences of Belarus, Chemical Series

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Extraction sample preparation for chromatographic determination of residual quantities of acidic penicillins in milk

https://doi.org/10.29235/1561-8331-2021-57-3-286-

Abstract

The distribution of six acid-type penicillins (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) in the extraction systems of chloroform–aqueous solutions of ammonium sulfate was studied. The reported distribution coefficients values of penicillins demonstrated the effectiveness of using ammonium sulfate as a salting-out agent. Based on the data obtained, a procedure for milk sample preparation was developed for the quantification of the residual content of six acid-type penicillins.

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ISSN 1561-8331 (Print)
ISSN 2524-2342 (Online)