Synthesis of 22- and 23-dehydroxybrassinosteroids of the stigmastane series
https://doi.org/10.29235/1561-8331-2023-59-3-202-210
Abstract
The synthesis of previously undescribed 22- and 23-deoxyanalogues of homocastasterone has been carried out, which makes it possible to obtain target compounds without replacing the carbon skeleton of the side chain. The key reactions in their synthesis were epoxy ring opening and radical debromination.
Supporting agencies: The work was financially supported by the Belarusian Republican Foundation for Fundamental Research (grant agreement no. X23RNF-087).
About the Authors
V. A. Khripach
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Khripach Vladimir A. – Academician, D. Sc. (Chemistry), Professor, Head of Laboratory
5/2, Kuprevich Str., 220084, Minsk
V. N. Zhabinskii
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Zhabinskii Vladimir N. – Corresponding Member of the National Academy of Sciences of Belarus, D. Sc. (Chemistry), Professor, Chief Researcher
5/2, Kuprevich Str., 220084, Minsk
E. V. Sikorov
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Sikorov Evgeny V. – Laboratory Assistant
5/2, Kuprevich Str., 220084, Minsk
S. I. Lazarev
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus
Belarus
Lazarev Stanislav I. – Junior Researcher
5/2, Kuprevich Str., 220084, Minsk
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