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SYNTHESIS OF ALIPHATIC ESTERS OF 5-AMINOLEVULINIC ACID AND THEIR EFFECT ON THE PHOTOTROPHIC MICROALGAE GROWTH

Abstract

Method for preparation of 5-aminolevulinic acid (ALA) aliphatic esters with aliphatic alcohols (С1–С16) is described. Melting points, spectral parameters and chromatographic characteristics for the esters obtained have been determined. Critical micelle concentration values of ALA hexyl ester and higher homologs in aqueous buffered system have been estimated. The stimulatory effect of micelle forming ALA esters at 0.1 mM concentration on the accumulation of phototrophic microalgae Chlorella and Scenedesmus obliquus dry biomass has been established (106–182% of the control).

About the Authors

A. L. Mikhalchuk
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus


E. V. Rudak
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus


P. V. Kurman
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus


S. V. Babitskaya
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus


M. A. Kisel
Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus
Belarus


N. K. Kalantaryan
Scientific and Production Center “Armbiotechnology” of the National Academy of Sciences of Republic of Armenia
Armenia


L. H. Saghatelyan
Scientific and Production Center “Armbiotechnology” of the National Academy of Sciences of Republic of Armenia
Armenia


V. B. Goginyan
Scientific and Production Center “Armbiotechnology” of the National Academy of Sciences of Republic of Armenia
Armenia


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ISSN 1561-8331 (Print)
ISSN 2524-2342 (Online)