Interaction of folic acid with silver nanoparticles
Abstract
The associates of folic acid (FA) with silver nanoparticles (SNPs) have been formed in situ, using FA both as the reducing agent for Ag (I) and for functionalization of SNPs formed, and also by FA physical adsorption on the previously prepared SNPs. FA effectively reduces Ag(I) to Ag0. Ultrasound accelerates the SNPs' synthesis and promotes formation of monodis-perse particles. SNPs are not formed in medium containing FA and NH3.H20. FA and the products of its oxidation associated with SNPs lose the ability of fluorescence. Isopropyl alcohol is the most efficient solvent for precipitation of FA(SNP) associates from the synthesis medium. SNPs and FA(SNP) associates do not reduce viability of Ehrlich's ascites carcinoma cells and mesenchymal stromal cells.
About the Authors
A. V. Abakshonok
Институт химии новых материалов НАН Беларуси
Belarus
Belarus
A. N. Eryomin
Институт химии новых материалов НАН Беларуси
Belarus
Belarus
V. E. Agabekov
Институт химии новых материалов НАН Беларуси
Belarus
Belarus
G. K. Zhavnerko
Институт химии новых материалов НАН Беларуси
Belarus
Belarus
E. A. Gracheva
Институт химии новых материалов НАН Беларуси
Belarus
Belarus
E. A. Petrova
Институт физиологии НАН Беларуси
Belarus
Belarus
T. I. Terpinskaya
Институт физиологии НАН Беларуси
Belarus
Belarus
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