Extraction of amitraz and its metabolites with organic solvents
https://doi.org/10.29235/1561-8331-2023-59-2-139-149
Abstract
The distribution constants of amitraz and its three main metabolites (DMFF, DMF, DMA) for water–organic solvent (n-hexane, toluene, dichloromethane, chloroform) extraction systems were estimated. Based on the analysis of the substances distribution in the studied systems, it was established that dichloromethane is the optimal choice for amitraz and its metabolites liquid-liquid extraction for method development for their simultaneous determination in honey. Amitraz stability study in water-acetonitrile solutions with various additives demonstrated that 50 mM ammonia solution in water– acetonitrile mixture (1 : 1, vol.) should be used as solvent for the samples final solutions.
About the Authors
A. G Polonevich
Belarusian State University; Scientific Practical Center of Hygiene
Belarus
Belarus
Anna G. Polonevich – doctoral student at the Department of Analytical Chemistry; Leading Chemist
14, Leningradskaya Str., 220030; 8, Akademicheskaya Str.,
220012, Minsk
S. M. Leschev
Belarusian State University
Belarus
Belarus
Sergey M. Leschev – Ph. D. (Chemistry), Professor
14, Leningradskaya Str., 220030
V. A. Bulhakava
Scientific Practical Center of Hygiene
Belarus
Belarus
Volha A. Bulhakava – chemist
8, Akademicheskaya Str., 220012, Minsk
L. L. Belysheva
Scientific Practical Center of Hygiene
Russian Federation
Russian Federation
Liudmila L. Belysheva – Head of the Laboratory
8, Akademicheskaya Str., 220012, Minsk
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