Extraction of para-hydroxybenzoic acid and parabens with organic solvents
https://doi.org/10.29235/1561-8331-2026-62-1-26-33
Abstract
Extraction of para-hydroxybenzoic acid and nine parabens (methylparaben, ethylparaben, propylparaben, iso-propylparaben, butylparaben, iso-butylparaben, pentylparaben, benzylparaben, phenylparaben) from their water solutions by organic solvents (n-hexane, chloroform, isoamyl alcohol) was studied. Analytes were quantified by high-performance liquid chromatography with diode-array detection. The distribution constants were calculated. The influence of the nature of extractants and the structure of the studied substances on the obtained values of the constants was analyzed. It was found that the values of the decimal logarithms of the distribution constants for para-hydroxybenzoic acid and parabens increase in the series n-hexane < chloroform < isoamyl alcohol, which corresponds to an increase in the extractive capacity of organic solvents.
About the Authors
E. V. Andrievskaya
Republican Center of Hygiene, Epidemiology and Public Health
Belarus
Belarus
Andrievskaya Ekaterina V. – Junior Researcher
8, Akademicheskay Str., 220012, Minsk
S. M. Leschev
Belarusian State University
Belarus
Belarus
Leschev Sergey M. – Dr. Sci. (Chemistry)
14, Leningradskaya Str., 220030, Minsk
A. I. Palianskikh
Republican Center of Hygiene, Epidemiology and Public Health
Belarus
Belarus
Palianskikh Alena I. – Ph. D. (Chemistry), Leading Researcher
8, Akademicheskay Str., 220012, Minsk
L. L. Belysheva
Republican Center of Hygiene, Epidemiology and Public Health
Belarus
Belarus
Belysheva Liudmila L. – Head of the Laboratory
8, Akademicheskay Str., 220012, Minsk
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