Bi_1-xNd_xFe_1-xMn_xO₃ solid solutions have been synthesized, their lattice constants have been determined and their dielectric properties have been studied. It has been established that substitution of bismuth and iron by neodymium and manganese, respectively, leads to the unit cell contraction of Bi_1-xNd_xFe_1-xMn_xO₃ solid solutions, increase of their electrical conductivity and, consequently, increase of their dielectric losses. Electrical conductivity activation energies for Bi_1-xNd_xFe_1-xMn_xO₃ de-crease with x , leading to the conclusion that joint substitutions Nd³⁺ → Bi³⁺ and Mn³⁺ → Fe³⁺ in BiFeO₃ facilitate the electri-cal transport in Bi_1-xNd_xFe_1-xMn_xO₃ solid solutions.

It has been found that in LaCo_1-xGa_xO₃ system increase of the substitution degree х from 0 to 0,95 leads to the gradual electrical conductivity (σ) decrease. Within 300-1050 K temperature range for samples LaCo_1-xGa_xO₃ with х ≤ 0,5 there are three linear parts on the curve lnσ - Т^-1, where electrical conductivity activation energies have been calculated for the low, intermediate and high temperature ranges. Electrical conductivity activation energy ( Е_А) for samples at different temperatures has been also estimated using derivatives^{d In σ}/_d(T-1). The E_A temperature dependence for LaCo_1-xGa_xO₃ at 0 ≤ х ≤ 0,5 passes through a maximum that indicates the temperature for beginning of semiconductor - metal phase transition (T_EA,max). It has been shown that the thermo-EMF coefficient (S) for LaCo_1-xGa_xO₃ (0,1 ≤ х ≤ 0,3) at room temperature is negative, increasing with temperature rising, going through zero at 435-530 K, reaching the maximum at 500-650 K and then dropping down. It has been established that the temperatures corresponding to the maximum S and Е_А values are identical.

For the first time, the template synthesis method has been used for controlling montmorillonite clay porous structure. Salts with varied hydration heats such as MgSO₄, Li₂SO₄, NiCl₂, RbNO₃, KCl, RbBr, have been used as templates. Their presence in swollen clay particles is accompanied by dehydration, leading to their interaction and formation of the structure having greater sorption capacity than acid-activated clay samples, its specific capacity being also increased several times. The main factors of the template effect on the improvement of montmorillonite clay structural parameters and ways of further development in this area, as well as properties of salt templates, destroying the solvent structure, and reasons for their low structure-forming ability, have been discussed.

The effect of the chemical nature of macromolecular surfactants and mixtures thereof upon their ability to form a first type dispersion with a long shelf life. Quality of dispersions prepared has been assessed by sedimentation analysis and rheological properties of the most promising formulations. High efficiency of some polymeric surfactants as emulsifiers for epoxy resins in aqueous media has been established.

Change in electrophoretic mobility and zeta potential of porous silica in divalent metal chloride water solutions has been discovered by microelectrophoresis. The probability of the electrostatic mechanism for ion exchange increases with the equilibrium cation concentration at the electrophoretic mobility zero point. When it decreases, electrostatic attraction gets assisted by a strong specific interaction. Smaller metal ions show high selectivity to the porous silica decreasing in the following order: Cu²⁺ ˃ Ni²⁺ ˃ Co²⁺ ˃ Zn²⁺.

Extraction of various classes of hydrophobic organochlorine pesticides (α, β, γ, δ, ε-hexachlorocyclohexane (HCH), 2,4’-,4,4’-DDT, 2,4’-,4,4’-DDE, 2,4’-, 4,4’-DDD, methoxychlor, hexachlorobenzene, heptachlor, aldrin, cis -, trans -heptachloroepoxide, dieldrin, endrin, endrin aldehyde, endrin ketone, endosulfan I, endosulfan II, endosulfan sulfate) by polar organic solvents (DMFA, DMSO, acetonitrile, ethylene glycol) or ionic liquid (1-butyl-3-methyl imidazolium acetate) has been studied. It has been established that DMFA is the most efficient solvent for group extraction of pesticides, while ethylene glycol is the least efficient one, while having the highest selectivity for extraction of HCH isomers. In practical terms, acetonitrile is the most convenient for extraction of organochlorine pesticides. The possibility of using extraction for additional identification of pollutants and for sampling of different environmental objects in GC-analysis has been illustrated.

The formation mechanism of perovskite-like layered compounds Sr₄Ni_1,8Me_0,1Ti_0,1O_x (Me - Mo, Ta, Nb) crystallizing in the Sr₃Ti₂O₇-type of structure has been investigated. It has been found that the limiting step is interaction of phases with the perovskite-type structure (Sr₉Ni₇O₂₁), K₂NiF₄ (Sr₂(Ti, Me)_mNi_1-mO_y) and SrO. Instability of oxides Sr₂(Ti, Me)_mNi_1-mO_y (Me - Mo, Ta, Nb) at synthesis temperatures determines the specific features of the mechanism and limiting stages, thereby opening the possibility for controlling the multistep solid state process.

In the process of 210-240 nm calcium alginate nanoparticles (AlgNP) non-emulsion synthesis from solutions with the 50-250-fold weight excess of stabilizers, polyethelyneglycol (PEG 1500) and Tween 80, as compared to polysaccharide, their molecules are incorporated in the forming gel in minimal concenrations (less than 64 ± 14 and 19 ± 9 mg/g on dry weight basis, accordingly). Their presence in solution decreases AlgNP size and stabilizes colloids. PEG 1500 macromolecules embedded into AlgNP slightly decrease gel polarity, while in AlgNP obtained with Tween 80, the local pockets formed by surfactant hydrophobic tails have been found.

Biphenyl-4-carboxylic acid arylhydrazones have been synthesized in aqueous medium under microwave activation. It has been shown that use of microwave irradiation reduces the reaction time and provides the product yield of 89-92 %. Biocidal properties of compounds prepared have been studied.

Methods for synthesis of new 1,2-diacyl-1-alkyl hydrazines, structurally related to known ecdysteroidal agonist methoxyfenozide, have been developed and their insecticidal effect on Colorado potato beetle larvae has been studied. The toxicity of one of synthesized compounds for the Colorado potato beetle has been found to be comparable to that of methoxyfenozide.

The method for preparation of new substituted arylcarboxylic acids containing the amino function, that are the key precursors for new functionally substituted amides, has been described.

The efficient method for synthesis of substituted 2-methylbenzofurans based on aromatization of 3-substituted-6-allylcyclohex-2-еnones in the presence of iodine with subsequent potassium hydroxide treatment of 2-iodomethyl-2,3-dihydro-benzofuran intermediates, has been described.

Derivatives of resveratrol and isoliquiritigenin (esters of acetic, benzoic and succinic acid) have been synthesized and characterized. The hydroxy group in 2^,-position of isoliquiritigenin is acylated more readily than at positions 4 and 4^, that can be explained by the influence of the intramolecular hydrogen bond. Isoliquiritigenin and its derivatives with free 2^,-hydroxyl undergo cycloisomerisation during gas chromatography analysis.

In order to study the catalytic properties of CYP1B1 toward a number of steroid compounds, we have developed an effective system of heterologous expression of hemoprotein in E.coli and isolated the preparation of recombinant CYP1B1 «soluble» form in a highly purified state. The interaction parameters of the purified enzyme with steroid ligands have been determined.

Β-Galactosylsphingosine a potential anti-HIV agent, has been prepared from pig brain cerebrosides and tested for antiviral activity. HIV-inhibitory properties of this compound, predicted previously by molecular modeling, have been confirmed. Consequently, the glycolipid obtained is considered as a promising basic structure for designing its more efficient derivatives.

The process of cellulose fiber esterification by dilute (0.3-0.8 mol/dm³) orthophosphoric acid water solutions in presence of urea under various conditions has been investigated. Low-substituted cellulose phosphates containing 0.25-0.5 mmol/g of phosphorus, have been prepared . Physical, chemical and medico-biological properties of cellulose phosphates obtained have been studied. It has been shown that they fit the medico-biological safety criteria, including biocompatibility indicators and possibility of use as medicine materials .

The fragment of phase diagram of polythersulfone - iso-propyl alcohol - dimethyl acetamide ternary system using the cloud point method, has been obtained. For the system studied, the upper critical solution temperature has been determined. Using the IR-spectroscopy, possibility of associate formation has been demonstrated.

It has been established that introduction of adhesives, containing groups reactive towards asphaltens, into the bitumen causes its colloid structure change. This in turn affects the irreversible change processes caused by air oxygen and elevated temperature. Maximal deceleration of thermo-oxidative destruction processes is effected by additives containing phosphate groups, either individually or together with amino groups, as the result of their interaction with bitumen asphaltens.

The chemical composition of essential oil from A. Concolor growing in urban environment has been studied, 48 ingredients being identified and their content measured. The results obtained demonstrate the relationship between certain ingredients’ content and envuironment pollution by toxic elements, that can be used as an indicator of the environment condition.

The possibility of controlling the potassium chloride structure formation under the dynamic conditions using water soluble polymer compositions and surfactants, has been experimentally shown. These compounds improve wetting, increase plastic strength, widen the optimal moisture content range in potassium chloride dispersion and increase strength of granules, as compared to individual components.