Imatinib, a selective BCR-ABL tyrosine kinase inhibitor has significantly improved efficacy of chronic myelogenous leukemia treatment. This review focuses on discovery and development of imatinib, methods of its synthesis and further structure optimization opportunities.

Methods for synthesis of m-terphenyl derivatives used as effective polymeric material stabilizers, food antioxidants, medicine preservatives have been discussed.

Excitation and photoluminescence spectra of La_0,997Pr_0,003InO₃, La_0,98Nd_0,02InO₃, La_0,977Pr_0,003Nd_0,02InO₃, La_0,977Pr_0,003Nd_0,02In_0,99Cr_0,01O₃, LaIn_,099Cr_0,01O₃ solid solutions have been studied. It has been found that Cr+ ions incorporated into the In³⁺+ sublattice of La_0,977Pr_0,003Nd_0,02In_0,99Cr_0,01O₃ solid solution can act as Nd³⁺ photoluminescence sensitizers under the excitation by visible light (λ = 445 nm).

Multiwall carbon nanotubes (MWCNTs), exhibiting high gas adsorption activity, have been prepared in the high voltage discharge plasma under atmospheric pressure from a mixture of hydrocarbons (methane, propane) and air. The structural characteristics of nanotubes have been studied by TEM. Composition WO₃ - MWNTs, prepared by sol-gel method, is of interest to create selective sensitive detectors of combustible gases. The greatest sensitivity to propane (≤ 500 %) has been observed at the substrate temperature below 200 °C, whereas high sensitivity to NO₂ (≤300 %) has been observed at higher temperatures (T - 240 °C and more).

The first attempt to determine the surface of micropores being blocked by adsorbate molecules, has been performed. The mechanism of blocked surface determination and its variations for micropores of varied sizes have been discussed. Equations for calculating the surface area of micropores blocked by adsorbate molecules, have been proposed. The blocked surface estimation variations for various micropore sizes have been noted. It has been shown that the formal application of BET method in this case does not give reliable information on the surface of the micropores, and mesoporous structure of the samples with a high content of micropores. Mesoporous structure of the sample in this case is formed from a microporous material with porosity not depending upon the surface of the mesopores, which is usually about 10-400 m²/g.

The paper deals with the problem of comparing the specific surface area determined by the BET method, and the geometric area. The cause of these discrepancies has been isolated and it has been shown that, depending on adsorbate molecules' packing type in the adsorption layer, the degree of divergence of the specific surface area determined by BET and geometric area of the solid, ranges between 10 and 20%.

The effect of industrial aluminium coagulants' composition and stirring intensity on characteristics of coagulates formed by hydrolysis, has been studied. Coagulates diameter and sedimentation rate have been established to be proportional to the aluminium polymeric species content in the coagulant, which is determined by its initial chemical composition. Formation of large coagulates has been shown to take place more rapidly at stirring intensity with velocity gradient value equal to 40 s^-1 (150 rpm). Both decreasing (to 9 s^-1, 50 rpm) and increasing (to 210-370 s^-1, 500-750 rpm) of stirring intensity led to coagulates' size decrease and their growth rate reduction.

By direct potentiometry with film Zn(NCS)^2-₄ -ISE and Co(NCS)^2-₄ -ISE based on higher quaternary ammonium salts, zinc and cobalt concentrations in beer, cheese, potatoes, soil have been determined. These electrodes are suitable for determination of zinc and cobalt in concentrations below the threshold limit value. Results of potentiometric determinations are in good agreement with results obtained by reference methods - atomic emission (AES) and atomic absorption spectrometry (AAS). The relative standard deviation of the potentiometric determination (S_{r pot^,} %) is lower than for AES or AAS results.

Electroless deposition of Ni-W-P films on silicon has been studied. The effect of the solution composition and operating parameters on Ni-W-P film deposition rate, microstructure and adhesion has been investigated and optimal conditions of alloy plating have been found. It has been shown that Ni-W-P films on thin Ni-P layers inhibits copper diffusion into silicon.

A new chlorine-free method for the synthesis of 8,9,12-Cl₃-1,2-C₂B₁₀H₉, including autoclave heating for 12 h in carbon tetrachloride in the presence of aluminum chloride at 140-150 °C has been suggested. The presence of 8-CHCl₂-9,12-Cl₂-1,2-C₂B₁₀H₉ in the reaction mixture has also been detected by GLC. Deborination of 8,9,12-Cl₃-1,2-C₂B₁₀H₉ and 8-CHCl₂-9,12-Cl₂-1,2-C₂B₁₀H₉ by alkali alcohol solution leads to nido-structures isolated as salts Me₄N+[1,5, 6-Cl₃-7,8-C₂B₉H₉]^- and Me₄N+[1-CHCl₂-5,6-Cl₂-7,8-C₂B₉H₉]^- with yields of 41% and 39%, respectively.

N-acetyl amino acids' (aminoacetic, β-alanine, ү-aminobutyriс, L-aspartic and L-glutamic) allyl esters have been synthesized. Physico-chemical characteristics of the esters have been determined. The рhosphorylated derivates of these allyl esters are of interest for pharmaceutical рurposes.

The possibility for development of new hemosorbents based on oligopeptide analogues of Staphylococcus aureus protein A epitopes and polyethylene matrix, is discussed. A convenient method for hemosorbent preparation has been developed and primary tests have been performed.

The synthesis of magnetic nanoparticles conjugated with oligonucleotides has been described. The conjugates prepared were used for immobilization of the model oligonucleotide sequence imitating the oncolytic RNA strand fragment.

It has been found that copper (II) migration into the aqueous phase from polyacrylonitrile fiber hydrolysate films containing copper sulfate (II) or copper (II) ethylenediaminetetraacetic acid disodium salt, slows down with increased branching of macromolecules. Prolongation effect is more pronounced for copper sulfate (II) due to the formation of copper macromo-lecular complex with carboxylate groups of the copolymer.

The tall pitch, modified by polyethylenepolyamine, has been prepared. Antimicrobic and anticorrosion properties of the product obtained, have been studied. The possibility of its use in impregnating compositions for protection of cable yarn and underground power cable, has been shown

The effects of chamomile and peppermint propylene glycol extracts mixed with extracted raw material, on physical and chemical parameters of cosmetic products as well as its resistance toward oxidation and microbiological spoilage. It has been established that the cosmetic product prepared with peppermint extracted, has the best properties. The technological production scheme of cosmetic products with plant extracts having improved consumer properties, has been proposed.

The specific features of precipitate formation and aging during neutralization in the CaO - H₃FO₄ - H₂SiF₆ - H₂O system in dilute solutions under nonequilibrium conditions, have been studied. It has been found that secondary chemical interaction occurs between the precipitate and solution, that changes their chemical composition and main technological properties of formed sludge. The mechanism for the aging process in the system, including hydrolysis and polymerization of some system components, have been proposed.

In thas paper the composition of indusrtial spent zinc-plating electrolytes was investigated and its zinc ions concentration was found. A way to obtain zinc phosphates that could be further used in pigment compositions from spent zinc-plating electrolytes was offered.

The brief overview of production and use of hexabromocyclododecane (HBCD) is given. HBCD is a persistent organic pollutant included in Stockholm Convention. The potential spheres of HBCD use in Belarus have been shown, the results of preliminary analysis of its flows into Belarus have been described. The potential manufacturing processes with HBCD use have been identified. Taking into account the international experience, the assessment of HBCD volume in styrofoams in Belarus is done.